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Free fatty acids induce ER stress and block antiviral activity of interferon alpha against hepatitis C virus in cell culture

Overview of attention for article published in Virology Journal, August 2012
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  • Good Attention Score compared to outputs of the same age and source (73rd percentile)

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3 X users

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41 Mendeley
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Title
Free fatty acids induce ER stress and block antiviral activity of interferon alpha against hepatitis C virus in cell culture
Published in
Virology Journal, August 2012
DOI 10.1186/1743-422x-9-143
Pubmed ID
Authors

Feyza Gunduz, Fatma M Aboulnasr, Partha K Chandra, Sidhartha Hazari, Bret Poat, Darren P Baker, Luis A Balart, Srikanta Dash

Abstract

Hepatic steatosis is recognized as a major risk factor for liver disease progression and impaired response to interferon based therapy in chronic hepatitis C (CHC) patients. The mechanism of response to interferon-alpha (IFN-α) therapy under the condition of hepatic steatosis is unexplored. We investigated the effect of hepatocellular steatosis on hepatitis C virus (HCV) replication and IFN-α antiviral response in a cell culture model.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Egypt 1 2%
Unknown 40 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 10 24%
Researcher 7 17%
Student > Ph. D. Student 6 15%
Student > Bachelor 5 12%
Student > Doctoral Student 2 5%
Other 7 17%
Unknown 4 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 34%
Medicine and Dentistry 7 17%
Immunology and Microbiology 5 12%
Biochemistry, Genetics and Molecular Biology 3 7%
Pharmacology, Toxicology and Pharmaceutical Science 2 5%
Other 5 12%
Unknown 5 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 August 2012.
All research outputs
#13,365,440
of 22,673,450 outputs
Outputs from Virology Journal
#1,350
of 3,029 outputs
Outputs of similar age
#90,709
of 164,731 outputs
Outputs of similar age from Virology Journal
#20
of 82 outputs
Altmetric has tracked 22,673,450 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,029 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.5. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,731 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 82 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.