You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Title |
Debate: The slippery slope of surrogate outcomes
|
---|---|
Published in |
Trials, October 2000
|
DOI | 10.1186/cvm-1-2-076 |
Pubmed ID | |
Authors |
Ralph B D'Agostino |
Abstract |
Surrogate outcomes are frequently used in cardiovascular disease research. A concern is that changes in surrogate markers may not reflect changes in disease outcomes. Two recent clinical trials (Heart and Estrogen/Progestin Replacement Study [HERS], and the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial [ALLHAT]) underscore this problem since their results contradicted what was expected based on the surrogate outcomes. The current regulatory policy to allow new therapies to be introduced onto the market based solely on surrogate outcomes may need to be reviewed. |
X Demographics
The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 2 | 50% |
Chile | 1 | 25% |
Unknown | 1 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 75% |
Scientists | 1 | 25% |
Mendeley readers
The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 3% |
Colombia | 1 | 3% |
Unknown | 28 | 93% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 20% |
Professor | 3 | 10% |
Student > Bachelor | 3 | 10% |
Student > Postgraduate | 3 | 10% |
Student > Ph. D. Student | 3 | 10% |
Other | 7 | 23% |
Unknown | 5 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 13 | 43% |
Biochemistry, Genetics and Molecular Biology | 2 | 7% |
Environmental Science | 1 | 3% |
Agricultural and Biological Sciences | 1 | 3% |
Chemical Engineering | 1 | 3% |
Other | 4 | 13% |
Unknown | 8 | 27% |