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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Roles of CREB in the regulation of FMRP by group I metabotropic glutamate receptors in cingulate cortex
|
|---|---|
| Published in |
Molecular Brain, August 2012
|
| DOI | 10.1186/1756-6606-5-27 |
| Pubmed ID | |
| Authors |
Hansen Wang, Yoshikazu Morishita, Daiki Miura, Jose R Naranjo, Satoshi Kida, Min Zhuo |
| Abstract |
Fragile X syndrome is caused by lack of fragile X mental retardation protein (FMRP) due to silencing of the FMR1 gene. The metabotropic glutamate receptors (mGluRs) in the central nervous system contribute to higher brain functions including learning/memory, mental disorders and persistent pain. The transcription factor cyclic AMP-responsive element binding protein (CREB) is involved in important neuronal functions, such as synaptic plasticity and neuronal survival. Our recent study has shown that stimulation of Group I mGluRs upregulated FMRP and activated CREB in anterior cingulate cortex (ACC), a key region for brain cognitive and executive functions, suggesting that activation of Group I mGluRs may upregulate FMRP through CREB signaling pathway. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Science communicators (journalists, bloggers, editors) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 5% |
| Unknown | 52 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 13 | 24% |
| Student > Bachelor | 9 | 16% |
| Researcher | 7 | 13% |
| Student > Master | 3 | 5% |
| Professor | 3 | 5% |
| Other | 9 | 16% |
| Unknown | 11 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 14 | 25% |
| Neuroscience | 9 | 16% |
| Medicine and Dentistry | 7 | 13% |
| Psychology | 7 | 13% |
| Biochemistry, Genetics and Molecular Biology | 5 | 9% |
| Other | 4 | 7% |
| Unknown | 9 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 August 2012.
All research outputs
#14,730,916
of 22,673,450 outputs
Outputs from Molecular Brain
#624
of 1,103 outputs
Outputs of similar age
#102,505
of 166,280 outputs
Outputs of similar age from Molecular Brain
#2
of 4 outputs
Altmetric has tracked 22,673,450 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,103 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 166,280 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.