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Compensatory substitutions in the HCV NS3/4A protease cleavage sites are not observed in patients treated unsuccessfully with telaprevir combination treatment

Overview of attention for article published in Virology Journal, August 2012
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Title
Compensatory substitutions in the HCV NS3/4A protease cleavage sites are not observed in patients treated unsuccessfully with telaprevir combination treatment
Published in
Virology Journal, August 2012
DOI 10.1186/1743-422x-9-147
Pubmed ID
Authors

James C Sullivan, Eileen Z Zhang, Doug J Bartels, Ann Tigges, Jennifer L Dorrian, Ann D Kwong, Tara L Kieffer

Abstract

Development of compensatory mutations within the HIV p7/p1 and p1/p6 protease cleavage site region has been observed in HIV-infected patients treated with protease inhibitors. Mechanisms of fitness compensation may occur in HCV populations upon treatment of HCV protease inhibitors as well.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Saudi Arabia 1 11%
Unknown 8 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 44%
Student > Ph. D. Student 2 22%
Professor 1 11%
Student > Bachelor 1 11%
Student > Postgraduate 1 11%
Other 0 0%
Readers by discipline Count As %
Medicine and Dentistry 5 56%
Agricultural and Biological Sciences 1 11%
Biochemistry, Genetics and Molecular Biology 1 11%
Neuroscience 1 11%
Engineering 1 11%
Other 0 0%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 August 2012.
All research outputs
#20,163,398
of 22,673,450 outputs
Outputs from Virology Journal
#2,863
of 3,029 outputs
Outputs of similar age
#149,080
of 166,280 outputs
Outputs of similar age from Virology Journal
#72
of 87 outputs
Altmetric has tracked 22,673,450 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,029 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 166,280 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 87 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.