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Characterisation of a natural variant of the γ-butyrolactone signalling receptor

Overview of attention for article published in BMC Research Notes, July 2012
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Title
Characterisation of a natural variant of the γ-butyrolactone signalling receptor
Published in
BMC Research Notes, July 2012
DOI 10.1186/1756-0500-5-379
Pubmed ID
Authors

Marco Gottelt, Andrew Hesketh, Robert Bunet, Pranav Puri, Eriko Takano

Abstract

The control of antibiotic production in Streptomyces coelicolor A3(2) involves complicated regulatory networks with multiple regulators controlling the expression of antibiotic biosynthetic pathways. One such regulatory network is that of the γ-butyrolactones, the so-called S. coelicolor butanolide (SCB) system. The γ-butyrolactones in this system serve as signalling molecules and bind to the receptor protein ScbR, releasing the repression of its target genes. The resulting expression changes affect the production of the two pigmented antibiotics Act and Red, as well as the transcription of the cpk antibiotic biosynthesis gene cluster and the synthesis of the γ-butyrolactones themselves.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 38 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 24%
Student > Ph. D. Student 8 21%
Student > Doctoral Student 5 13%
Student > Master 4 11%
Student > Bachelor 2 5%
Other 4 11%
Unknown 6 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 11 29%
Agricultural and Biological Sciences 10 26%
Chemistry 5 13%
Psychology 1 3%
Immunology and Microbiology 1 3%
Other 2 5%
Unknown 8 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 August 2012.
All research outputs
#18,312,024
of 22,673,450 outputs
Outputs from BMC Research Notes
#3,006
of 4,250 outputs
Outputs of similar age
#126,119
of 164,673 outputs
Outputs of similar age from BMC Research Notes
#82
of 109 outputs
Altmetric has tracked 22,673,450 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,250 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,673 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 109 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.