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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Signaling in colon cancer stem cells
|
|---|---|
| Published in |
Journal of Molecular Signaling, August 2012
|
| DOI | 10.1186/1750-2187-7-11 |
| Pubmed ID | |
| Authors |
Sanchita Roy, Adhip PN Majumdar |
| Abstract |
: Colorectal cancer is the fourth most common form of cancer worldwide and ranks third among the cancer-related deaths in the US and other Western countries. It occurs with equal frequency in men and women, constituting 10% of new cancer cases in men and 11% in women. Despite recent advancement in therapeutics, the survival rates from metastatic are less than 5%. Growing evidence supports the contention that epithelial cancers including colorectal cancer, the incidence of which increases with aging, are diseases driven by the pluripotent, self-renewing cancer stem cells (CSCs). Dysregulation of Wnt, Notch, Hedgehog and/or TGF-β signaling pathways that are involved in proliferation and maintenance of CSCs leads to the development of CRC. This review focuses on the signaling pathways relevant for CRC to understand the mechanisms leading to tumor progression and therapy resistance, which may help in the development of therapeutic strategies for CRC. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 91 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 4% |
| Iran, Islamic Republic of | 2 | 2% |
| Sweden | 1 | 1% |
| Germany | 1 | 1% |
| Luxembourg | 1 | 1% |
| Unknown | 82 | 90% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 33 | 36% |
| Student > Master | 16 | 18% |
| Researcher | 12 | 13% |
| Student > Bachelor | 9 | 10% |
| Student > Doctoral Student | 4 | 4% |
| Other | 7 | 8% |
| Unknown | 10 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 41 | 45% |
| Biochemistry, Genetics and Molecular Biology | 20 | 22% |
| Medicine and Dentistry | 15 | 16% |
| Computer Science | 1 | 1% |
| Nursing and Health Professions | 1 | 1% |
| Other | 0 | 0% |
| Unknown | 13 | 14% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 August 2012.
All research outputs
#18,312,024
of 22,673,450 outputs
Outputs from Journal of Molecular Signaling
#33
of 44 outputs
Outputs of similar age
#127,601
of 166,280 outputs
Outputs of similar age from Journal of Molecular Signaling
#4
of 5 outputs
Altmetric has tracked 22,673,450 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 44 research outputs from this source. They receive a mean Attention Score of 2.6. This one scored the same or higher as 11 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 166,280 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one.