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Mendeley readers
| Title |
Validation of a single biopsy approach and bolus protein feeding to determine myofibrillar protein synthesis in stable isotope tracer studies in humans
|
|---|---|
| Published in |
Nutrition & Metabolism, March 2011
|
| DOI | 10.1186/1743-7075-8-15 |
| Pubmed ID | |
| Authors |
Nicholas A Burd, Daniel WD West, Tracy Rerecich, Todd Prior, Steven K Baker, Stuart M Phillips |
| Abstract |
Minimizing the number of muscle biopsies has important methodological implications and minimizes subject discomfort during a stable isotope amino acid infusion. We aimed to determine the reliability of obtaining a single muscle biopsy for the calculation of muscle protein fractional synthetic rate (FSR) as well as the amount of incorporation time necessary to obtain that biopsy after initiating a stable isotope infusion (Study 1). The calculation of muscle protein FSR requires tracer steady-state during the stable isotope infusion. Therefore, a second aim was to examine if steady-state conditions are compromised in the precursor pools (plasma free or muscle intracellular [IC]) after ingestion of a tracer enriched protein drink and after resistance exercise (Study 2). |
Mendeley readers
The data shown below were compiled from readership statistics for 90 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Denmark | 3 | 3% |
| United Kingdom | 2 | 2% |
| United States | 1 | 1% |
| Unknown | 84 | 93% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 23% |
| Student > Bachelor | 12 | 13% |
| Researcher | 11 | 12% |
| Student > Master | 8 | 9% |
| Student > Doctoral Student | 8 | 9% |
| Other | 20 | 22% |
| Unknown | 10 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 21 | 23% |
| Agricultural and Biological Sciences | 18 | 20% |
| Sports and Recreations | 18 | 20% |
| Nursing and Health Professions | 9 | 10% |
| Biochemistry, Genetics and Molecular Biology | 7 | 8% |
| Other | 5 | 6% |
| Unknown | 12 | 13% |