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Co-administration of avian influenza virus H5 plasmid DNA with chicken IL-15 and IL-18 enhanced chickens immune responses

Overview of attention for article published in BMC Veterinary Research, August 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • Good Attention Score compared to outputs of the same age and source (79th percentile)

Mentioned by

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1 X user
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2 patents

Citations

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28 Dimensions

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49 Mendeley
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Title
Co-administration of avian influenza virus H5 plasmid DNA with chicken IL-15 and IL-18 enhanced chickens immune responses
Published in
BMC Veterinary Research, August 2012
DOI 10.1186/1746-6148-8-132
Pubmed ID
Authors

Kian-Lam Lim, Seyed Davoud Jazayeri, Swee Keong Yeap, Noorjahan Banu Mohamed Alitheen, Mohd Hair Bejo, Aini Ideris, Abdul Rahman Omar

Abstract

DNA vaccines offer several advantages over conventional vaccines in the development of effective vaccines against avian influenza virus (AIV). However, one of the limitations of the DNA vaccine in poultry is that it induces poor immune responses. In this study, chicken interleukin (IL) -15 and IL-18 were used as genetic adjuvants to improve the immune responses induced from the H5 DNA vaccination in chickens. The immunogenicity of the recombinant plasmid DNA was analyzed based on the antibody production, T cell responses and cytokine production, following inoculation in 1-day-old (Trial 1) and 14-day-old (Trial 2) specific-pathogen-free chickens. Hence, the purpose of the present study was to explore the role of chicken IL-15 and IL-18 as adjuvants following the vaccination of chickens with the H5 DNA vaccine.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Malaysia 1 2%
Mexico 1 2%
Denmark 1 2%
Unknown 46 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 27%
Researcher 10 20%
Student > Master 7 14%
Student > Bachelor 5 10%
Professor 2 4%
Other 4 8%
Unknown 8 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 35%
Biochemistry, Genetics and Molecular Biology 7 14%
Medicine and Dentistry 5 10%
Immunology and Microbiology 5 10%
Veterinary Science and Veterinary Medicine 3 6%
Other 3 6%
Unknown 9 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 September 2019.
All research outputs
#4,486,111
of 22,673,450 outputs
Outputs from BMC Veterinary Research
#327
of 3,031 outputs
Outputs of similar age
#31,381
of 166,280 outputs
Outputs of similar age from BMC Veterinary Research
#7
of 34 outputs
Altmetric has tracked 22,673,450 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,031 research outputs from this source. They receive a mean Attention Score of 3.8. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 166,280 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.