Title |
Diagnostic and economic evaluation of new biomarkers for Alzheimer’s disease: the research protocol of a prospective cohort study
|
---|---|
Published in |
BMC Neurology, August 2012
|
DOI | 10.1186/1471-2377-12-72 |
Pubmed ID | |
Authors |
Ron LH Handels, Pauline Aalten, Claire AG Wolfs, Marcel OldeRikkert, Philip Scheltens, Pieter Jelle Visser, Manuela A Joore, Johan L Severens, Frans RJ Verhey |
Abstract |
New research criteria for the diagnosis of Alzheimer's disease (AD) have recently been developed to enable an early diagnosis of AD pathophysiology by relying on emerging biomarkers. To enable efficient allocation of health care resources, evidence is needed to support decision makers on the adoption of emerging biomarkers in clinical practice. The research goals are to 1) assess the diagnostic test accuracy of current clinical diagnostic work-up and emerging biomarkers in MRI, PET and CSF, 2) perform a cost-consequence analysis and 3) assess long-term cost-effectiveness by an economic model. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Egypt | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 4 | 3% |
Cuba | 1 | <1% |
Netherlands | 1 | <1% |
Spain | 1 | <1% |
Australia | 1 | <1% |
Unknown | 129 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 27 | 20% |
Researcher | 21 | 15% |
Student > Master | 19 | 14% |
Student > Bachelor | 9 | 7% |
Other | 7 | 5% |
Other | 17 | 12% |
Unknown | 37 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 19 | 14% |
Medicine and Dentistry | 19 | 14% |
Neuroscience | 11 | 8% |
Agricultural and Biological Sciences | 8 | 6% |
Nursing and Health Professions | 7 | 5% |
Other | 23 | 17% |
Unknown | 50 | 36% |