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Characterization of microRNA expression profiles in normal and osteoarthritic human chondrocytes

Overview of attention for article published in BMC Musculoskeletal Disorders, August 2012
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Title
Characterization of microRNA expression profiles in normal and osteoarthritic human chondrocytes
Published in
BMC Musculoskeletal Disorders, August 2012
DOI 10.1186/1471-2474-13-144
Pubmed ID
Authors

Silvia Díaz-Prado, Claudia Cicione, Emma Muiños-López, Tamara Hermida-Gómez, Natividad Oreiro, Carlos Fernández-López, Francisco J Blanco

Abstract

Osteoarthritis (OA) is a multifactorial disease characterized by destruction of the articular cartilage due to environmental, mechanical and genetic components. The genetics of OA is complex and is not completely understood. Recent works have demonstrated the importance of microRNAs (miRNAs) in cartilage function. MiRNAs are a class of small noncoding RNAs that regulate gene expression and are involved in different cellular process: apoptosis, proliferation, development, glucose and lipid metabolism. The aim of this study was to identify and characterize the expression profile of miRNAs in normal and OA chondrocytes and to determine their role in the OA.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 97 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Spain 1 1%
Germany 1 1%
Unknown 94 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 23 24%
Student > Ph. D. Student 18 19%
Student > Master 7 7%
Student > Bachelor 7 7%
Student > Doctoral Student 5 5%
Other 18 19%
Unknown 19 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 21%
Biochemistry, Genetics and Molecular Biology 19 20%
Medicine and Dentistry 17 18%
Veterinary Science and Veterinary Medicine 3 3%
Pharmacology, Toxicology and Pharmaceutical Science 2 2%
Other 9 9%
Unknown 27 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 August 2012.
All research outputs
#15,248,503
of 22,673,450 outputs
Outputs from BMC Musculoskeletal Disorders
#2,443
of 4,024 outputs
Outputs of similar age
#106,775
of 167,577 outputs
Outputs of similar age from BMC Musculoskeletal Disorders
#41
of 61 outputs
Altmetric has tracked 22,673,450 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,024 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one is in the 28th percentile – i.e., 28% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 167,577 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 61 others from the same source and published within six weeks on either side of this one. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.