Title |
Patient-controlled encrypted genomic data: an approach to advance clinical genomics
|
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Published in |
BMC Medical Genomics, July 2012
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DOI | 10.1186/1755-8794-5-31 |
Pubmed ID | |
Authors |
Yannis J Trakadis |
Abstract |
The revolution in DNA sequencing technologies over the past decade has made it feasible to sequence an individual's whole genome at a relatively low cost. The potential value of the information generated by genomic technologies for medicine and society is enormous. However, in order for exome sequencing, and eventually whole genome sequencing, to be implemented clinically, a number of major challenges need to be overcome. For instance, obtaining meaningful informed-consent, managing incidental findings and the great volume of data generated (including multiple findings with uncertain clinical significance), re-interpreting the genomic data and providing additional counselling to patients as genetic knowledge evolves are issues that need to be addressed. It appears that medical genetics is shifting from the present "phenotype-first" medical model to a "data-first" model which leads to multiple complexities. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | 2% |
Sweden | 1 | 2% |
United Kingdom | 1 | 2% |
Canada | 1 | 2% |
United States | 1 | 2% |
Unknown | 39 | 89% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 15 | 34% |
Student > Master | 8 | 18% |
Student > Ph. D. Student | 4 | 9% |
Student > Doctoral Student | 3 | 7% |
Other | 3 | 7% |
Other | 9 | 20% |
Unknown | 2 | 5% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 14 | 32% |
Agricultural and Biological Sciences | 12 | 27% |
Computer Science | 4 | 9% |
Biochemistry, Genetics and Molecular Biology | 2 | 5% |
Social Sciences | 2 | 5% |
Other | 5 | 11% |
Unknown | 5 | 11% |