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Reconstructing DNA copy number by joint segmentation of multiple sequences

Overview of attention for article published in BMC Bioinformatics, August 2012
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Title
Reconstructing DNA copy number by joint segmentation of multiple sequences
Published in
BMC Bioinformatics, August 2012
DOI 10.1186/1471-2105-13-205
Pubmed ID
Authors

Zhongyang Zhang, Kenneth Lange, Chiara Sabatti

Abstract

Variations in DNA copy number carry information on the modalities of genome evolution and mis-regulation of DNA replication in cancer cells. Their study can help localize tumor suppressor genes, distinguish different populations of cancerous cells, and identify genomic variations responsible for disease phenotypes. A number of different high throughput technologies can be used to identify copy number variable sites, and the literature documents multiple effective algorithms. We focus here on the specific problem of detecting regions where variation in copy number is relatively common in the sample at hand. This problem encompasses the cases of copy number polymorphisms, related samples, technical replicates, and cancerous sub-populations from the same individual.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 6%
Unknown 32 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 24%
Student > Ph. D. Student 8 24%
Student > Master 4 12%
Other 3 9%
Student > Doctoral Student 1 3%
Other 4 12%
Unknown 6 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 26%
Computer Science 7 21%
Biochemistry, Genetics and Molecular Biology 4 12%
Medicine and Dentistry 4 12%
Mathematics 3 9%
Other 1 3%
Unknown 6 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 May 2013.
All research outputs
#15,248,503
of 22,673,450 outputs
Outputs from BMC Bioinformatics
#5,361
of 7,249 outputs
Outputs of similar age
#95,339
of 149,519 outputs
Outputs of similar age from BMC Bioinformatics
#64
of 101 outputs
Altmetric has tracked 22,673,450 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,249 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 149,519 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 101 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.