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Dystrophic neurites express C9orf72 in Alzheimer's disease brains

Overview of attention for article published in Alzheimer's Research & Therapy, January 2012
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (67th percentile)

Mentioned by

twitter
1 tweeter
patent
5 patents

Citations

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18 Dimensions

Readers on

mendeley
61 Mendeley
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Title
Dystrophic neurites express C9orf72 in Alzheimer's disease brains
Published in
Alzheimer's Research & Therapy, January 2012
DOI 10.1186/alzrt136
Pubmed ID
Authors

Jun-ichi Satoh, Hiroko Tabunoki, Tsuyoshi Ishida, Yuko Saito, Kunimasa Arima

Abstract

Chromosome 9 open reading frame 72 (C9orf72) is an evolutionarily conserved protein with unknown function, expressed at high levels in the brain. An expanded hexanucleotide GGGGCC repeat located in the first intron of the C9orf72 gene represents the most common genetic cause of familial frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). Previous studies by immunohistochemistry with two different anti-C9orf72 antibodies named sc-138763 and HPA023873 showed that C9orf72 is expressed chiefly in the cytoplasm of neurons, and is concentrated in the synaptic terminals in the brains of FTD/ALS with or without C9orf72 repeat expansion as well as those of controls. At present, a pathological role of C9orf72 in the process of neurodegeneration remains unknown.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
Spain 1 2%
United Kingdom 1 2%
Unknown 57 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 20%
Researcher 9 15%
Student > Doctoral Student 8 13%
Student > Master 6 10%
Other 5 8%
Other 9 15%
Unknown 12 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 22 36%
Neuroscience 10 16%
Medicine and Dentistry 7 11%
Biochemistry, Genetics and Molecular Biology 6 10%
Psychology 1 2%
Other 2 3%
Unknown 13 21%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 June 2021.
All research outputs
#6,688,923
of 21,339,393 outputs
Outputs from Alzheimer's Research & Therapy
#920
of 1,101 outputs
Outputs of similar age
#46,743
of 148,146 outputs
Outputs of similar age from Alzheimer's Research & Therapy
#1
of 1 outputs
Altmetric has tracked 21,339,393 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 1,101 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 23.1. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 148,146 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them