Title |
Discovery and functional characterization of two diterpene synthases for sclareol biosynthesis in Salvia sclarea(L.) and their relevance for perfume manufacture
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Published in |
BMC Plant Biology, July 2012
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DOI | 10.1186/1471-2229-12-119 |
Pubmed ID | |
Authors |
Anne Caniard, Philipp Zerbe, Sylvain Legrand, Allison Cohade, Nadine Valot, Jean-Louis Magnard, Jörg Bohlmann, Laurent Legendre |
Abstract |
Sclareol is a diterpene natural product of high value for the fragrance industry. Its labdane carbon skeleton and its two hydroxyl groups also make it a valued starting material for semisynthesis of numerous commercial substances, including production of Ambrox® and related ambergris substitutes used in the formulation of high end perfumes. Most of the commercially-produced sclareol is derived from cultivated clary sage (Salvia sclarea) and extraction of the plant material. In clary sage, sclareol mainly accumulates in essential oil-producing trichomes that densely cover flower calices. Manool also is a minor diterpene of this species and the main diterpene of related Salvia species. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 2 | 1% |
Austria | 1 | <1% |
Canada | 1 | <1% |
United States | 1 | <1% |
Serbia | 1 | <1% |
Unknown | 192 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 41 | 21% |
Researcher | 36 | 18% |
Student > Master | 28 | 14% |
Student > Bachelor | 22 | 11% |
Student > Postgraduate | 9 | 5% |
Other | 23 | 12% |
Unknown | 39 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 83 | 42% |
Biochemistry, Genetics and Molecular Biology | 40 | 20% |
Chemistry | 11 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 6 | 3% |
Engineering | 4 | 2% |
Other | 17 | 9% |
Unknown | 37 | 19% |