In early Alzheimer’s, amyloid, tau, inflammation & iron all cause tiny microstructural changes in the brain. I have previously shown that early stages of disease can be detected by measuring ‘heterogeneity’ of #MRI signal across the #hippocampus. 🔌ht
Early detection of brain changes in neurodegenerative disease is critical for developing effective treatments. We previously found that heterogeneity of T2 signal in the hippocampus may signal damage better than the average T2 signal, or volume: https://
At 9pm (GMT) today, I'll be speaking about our work using structural MRI to spot early signs of Alzheimer's. Paper: https://t.co/gDduiHgP5m Sure it's a bit late in the day - but you're allowed to bring wine. Perhaps I'll have some too Register (free):
Our recently published paper on a potential new early marker of neurodegenerative disease has been accessed 999 times As great as this is, it's also giving me anxiety so could 1 more person please read the paper ok thanks https://t.co/gDduiHgP5m (Thread