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Bacteriophage infections of microbiota can lead to leaky gut in an experimental rodent model

Overview of attention for article published in Gut Pathogens, June 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#2 of 423)
  • High Attention Score compared to outputs of the same age (99th percentile)

Mentioned by

news
65 news outlets
blogs
2 blogs
twitter
25 tweeters
facebook
4 Facebook pages
googleplus
1 Google+ user
reddit
1 Redditor

Citations

dimensions_citation
47 Dimensions

Readers on

mendeley
121 Mendeley
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Title
Bacteriophage infections of microbiota can lead to leaky gut in an experimental rodent model
Published in
Gut Pathogens, June 2016
DOI 10.1186/s13099-016-0109-1
Pubmed ID
Authors

George Tetz, Victor Tetz

Abstract

Increased intestinal permeability and translocation of gut microbiota from the intestinal lumen to the systemic circulation predispose patients to various diseases and may be one of the main triggers thereof. The role of microbiota in increased intestinal permeability is under intensive investigation. Here, we studied alterations in the host and increased intestinal permeability as a direct effect of treatment with a bacteriophage cocktail. After 10 days of challenge, the rats showed weight loss, messy hair, and decreased activity. Additionally, they displayed a significantly elevated lactulose:mannitol ratio and the level of circulating immune complexes. To our knowledge, this study demonstrates for the first time that increased intestinal permeability may be induced by bacteriophages that affect the microbiota.

Twitter Demographics

The data shown below were collected from the profiles of 25 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 121 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Nepal 1 <1%
United States 1 <1%
Sweden 1 <1%
France 1 <1%
Unknown 117 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 23 19%
Student > Ph. D. Student 20 17%
Researcher 19 16%
Student > Master 11 9%
Professor 6 5%
Other 18 15%
Unknown 24 20%
Readers by discipline Count As %
Immunology and Microbiology 20 17%
Biochemistry, Genetics and Molecular Biology 19 16%
Agricultural and Biological Sciences 19 16%
Medicine and Dentistry 8 7%
Pharmacology, Toxicology and Pharmaceutical Science 5 4%
Other 19 16%
Unknown 31 26%

Attention Score in Context

This research output has an Altmetric Attention Score of 526. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 June 2019.
All research outputs
#25,203
of 17,651,001 outputs
Outputs from Gut Pathogens
#2
of 423 outputs
Outputs of similar age
#784
of 269,512 outputs
Outputs of similar age from Gut Pathogens
#1
of 1 outputs
Altmetric has tracked 17,651,001 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 423 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.9. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 269,512 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them