Title |
Visualisation of cerebrospinal fluid flow patterns in albino Xenopus larvae in vivo
|
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Published in |
Fluids and Barriers of the CNS, April 2012
|
DOI | 10.1186/2045-8118-9-9 |
Pubmed ID | |
Authors |
Kazue Mogi, Takeshi Adachi, Susumu Izumi, Ryuji Toyoizumi |
Abstract |
It has long been known that cerebrospinal fluid (CSF), its composition and flow, play an important part in normal brain development, and ependymal cell ciliary beating as a possible driver of CSF flow has previously been studied in mammalian fetuses in vitro. Lower vertebrate animals are potential models for analysis of CSF flow during development because they are oviparous. Albino Xenopus laevis larvae are nearly transparent and have a straight, translucent brain that facilitates the observation of fluid flow within the ventricles. The aim of these experiments was to study CSF flow and circulation in vivo in the developing brain of living embryos, larvae and tadpoles of Xenopus laevis using a microinjection technique. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 2% |
Unknown | 49 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 11 | 22% |
Student > Bachelor | 8 | 16% |
Student > Ph. D. Student | 7 | 14% |
Student > Doctoral Student | 3 | 6% |
Student > Postgraduate | 2 | 4% |
Other | 5 | 10% |
Unknown | 14 | 28% |
Readers by discipline | Count | As % |
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Engineering | 2 | 4% |
Other | 6 | 12% |
Unknown | 16 | 32% |