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Application prospective of nanoprobes with MRI and FI dual-modality imaging on breast cancer stem cells in tumor

Overview of attention for article published in Journal of Nanobiotechnology, June 2016
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Title
Application prospective of nanoprobes with MRI and FI dual-modality imaging on breast cancer stem cells in tumor
Published in
Journal of Nanobiotechnology, June 2016
DOI 10.1186/s12951-016-0195-8
Pubmed ID
Authors

Hetao Chen, Yu Wang, Tong Wang, Dongxing Shi, Zengrong Sun, Chunhui Xia, Baiqi Wang

Abstract

Breast cancer (BC) is a serious disease to threat lives of women. Numerous studies have proved that BC originates from cancer stem cells (CSCs). But at present, no one approach can quickly and simply identify breast cancer stem cells (BCSCs) in solid tumor. Nanotechnology is probably able to realize this goal. But in study process, scientists find it seems that nanomaterials with one modality, such as magnetic resonance imaging (MRI) or fluorescence imaging (FI), have their own advantages and drawbacks. They cannot meet practical requirements in clinic. The nanoprobe combined MRI with FI modality is a promising tool to accurately detect desired cells with low amount in tissue. In this work, we briefly describe the MRI and FI development history, analyze advantages and disadvantages of nanomaterials with single modality in cancer cell detection. Then the application development of nanomaterials with dual-modality in cancer field is discussed. Finally, the obstacles and prospective of dual-modal nanoparticles in detection field of BCSCs are also pointed out in order to speed up clinical applications of nanoprobes.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 4%
Japan 1 4%
Unknown 22 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 29%
Student > Master 6 25%
Student > Bachelor 3 13%
Student > Doctoral Student 2 8%
Lecturer 1 4%
Other 1 4%
Unknown 4 17%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 17%
Chemistry 4 17%
Engineering 3 13%
Medicine and Dentistry 3 13%
Agricultural and Biological Sciences 2 8%
Other 3 13%
Unknown 5 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 July 2016.
All research outputs
#14,267,420
of 22,879,161 outputs
Outputs from Journal of Nanobiotechnology
#505
of 1,423 outputs
Outputs of similar age
#201,713
of 352,801 outputs
Outputs of similar age from Journal of Nanobiotechnology
#8
of 16 outputs
Altmetric has tracked 22,879,161 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,423 research outputs from this source. They receive a mean Attention Score of 3.5. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 352,801 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.