Title |
Infection with street strain rabies virus induces modulation of the microRNA profile of the mouse brain
|
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Published in |
Virology Journal, August 2012
|
DOI | 10.1186/1743-422x-9-159 |
Pubmed ID | |
Authors |
Pingsen Zhao, Lili Zhao, Kun Zhang, Hao Feng, Hualei Wang, Tiecheng Wang, Tao Xu, Na Feng, Chengyu Wang, Yuwei Gao, Geng Huang, Chuan Qin, Songtao Yang, Xianzhu Xia |
Abstract |
Rabies virus (RABV) causes a fatal infection of the central nervous systems (CNS) of warm-blooded animals. Once the clinical symptoms develop, rabies is almost invariably fatal. The mechanism of RABV pathogenesis remains poorly understood. Recent studies have shown that microRNA (miRNA) plays an important role in the pathogenesis of viral infections. Our recent findings have revealed that infection with laboratory-fixed rabies virus strain can induce modulation of the microRNA profile of mouse brains. However, no previous report has evaluated the miRNA expression profile of mouse brains infected with RABV street strain. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 2% |
Unknown | 41 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 9 | 21% |
Researcher | 8 | 19% |
Student > Ph. D. Student | 5 | 12% |
Professor > Associate Professor | 5 | 12% |
Student > Bachelor | 3 | 7% |
Other | 3 | 7% |
Unknown | 9 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 14 | 33% |
Biochemistry, Genetics and Molecular Biology | 6 | 14% |
Veterinary Science and Veterinary Medicine | 3 | 7% |
Immunology and Microbiology | 3 | 7% |
Medicine and Dentistry | 2 | 5% |
Other | 5 | 12% |
Unknown | 9 | 21% |