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Particulate matter air pollution disrupts endothelial cell barrier via calpain-mediated tight junction protein degradation

Overview of attention for article published in Particle and Fibre Toxicology, August 2012
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Title
Particulate matter air pollution disrupts endothelial cell barrier via calpain-mediated tight junction protein degradation
Published in
Particle and Fibre Toxicology, August 2012
DOI 10.1186/1743-8977-9-35
Pubmed ID
Authors

Ting Wang, Lichun Wang, Liliana Moreno-Vinasco, Gabriel D Lang, Jessica H Siegler, Biji Mathew, Peter V Usatyuk, Jonathan M Samet, Alison S Geyh, Patrick N Breysse, Viswanathan Natarajan, Joe G N Garcia

Abstract

Exposure to particulate matter (PM) is a significant risk factor for increased cardiopulmonary morbidity and mortality. The mechanism of PM-mediated pathophysiology remains unknown. However, PM is proinflammatory to the endothelium and increases vascular permeability in vitro and in vivo via ROS generation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 76 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Unknown 75 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 21%
Researcher 12 16%
Student > Master 11 14%
Student > Bachelor 7 9%
Professor > Associate Professor 6 8%
Other 15 20%
Unknown 9 12%
Readers by discipline Count As %
Medicine and Dentistry 15 20%
Agricultural and Biological Sciences 14 18%
Biochemistry, Genetics and Molecular Biology 7 9%
Environmental Science 5 7%
Pharmacology, Toxicology and Pharmaceutical Science 3 4%
Other 15 20%
Unknown 17 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 September 2023.
All research outputs
#17,299,378
of 25,391,701 outputs
Outputs from Particle and Fibre Toxicology
#435
of 615 outputs
Outputs of similar age
#125,068
of 187,976 outputs
Outputs of similar age from Particle and Fibre Toxicology
#5
of 6 outputs
Altmetric has tracked 25,391,701 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 615 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.2. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 187,976 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one.