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The influence of environmental variables on platelet concentration in horse platelet-rich plasma

Overview of attention for article published in Acta Veterinaria Scandinavica, July 2016
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Title
The influence of environmental variables on platelet concentration in horse platelet-rich plasma
Published in
Acta Veterinaria Scandinavica, July 2016
DOI 10.1186/s13028-016-0226-3
Pubmed ID
Authors

Riccardo Rinnovati, Noemi Romagnoli, Fabio Gentilini, Carlotta Lambertini, Alessandro Spadari

Abstract

Platelet-rich plasma (PRP) commonly refers to blood products which contain a higher platelet (PLT) concentration as compared to normal plasma. Autologous PRP has been shown to be safe and effective in promoting the natural processes of soft tissue healing or reconstruction in humans and horses. Variability in PLT concentration has been observed in practice between PRP preparations from different patients or from the same individual under different conditions. A change in PLT concentration could modify PRP efficacy in routine applications. The aim of this study was to test the influence of environmental, individual and agonistic variables on the PLT concentration of PRP in horses. Six healthy Standardbred mares were exposed to six different variables with a one-week washout period between variables, and PRP was subsequently obtained from each horse. The variables were time of withdrawal during the day (morning/evening), hydration status (overhydration/dehydration) treatment with anti-inflammatory drugs and training periods on a treadmill. The platelet concentration was significantly higher in horses treated with a non-steroidal anti-inflammatory drug (P = 0.03). The leukocyte concentration increased 2-9 fold with respect to whole blood in the PRP which was obtained after exposure to all the variable considered. Environmental variation in platelet concentration should be taken into consideration during PRP preparation.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 44 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 9 20%
Researcher 7 16%
Student > Postgraduate 4 9%
Student > Doctoral Student 3 7%
Professor 2 5%
Other 9 20%
Unknown 10 23%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 16 36%
Medicine and Dentistry 6 14%
Agricultural and Biological Sciences 4 9%
Biochemistry, Genetics and Molecular Biology 3 7%
Arts and Humanities 1 2%
Other 3 7%
Unknown 11 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 July 2016.
All research outputs
#16,579,551
of 25,373,627 outputs
Outputs from Acta Veterinaria Scandinavica
#393
of 837 outputs
Outputs of similar age
#227,666
of 369,846 outputs
Outputs of similar age from Acta Veterinaria Scandinavica
#5
of 16 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 837 research outputs from this source. They receive a mean Attention Score of 3.4. This one has gotten more attention than average, scoring higher than 52% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 369,846 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.