Title |
Pharmacokinetics and effect of intravenous meloxicam in weaned Holstein calves following scoop dehorning without local anesthesia
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Published in |
BMC Veterinary Research, September 2012
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DOI | 10.1186/1746-6148-8-153 |
Pubmed ID | |
Authors |
Johann F Coetzee, Ruby A Mosher, Butch KuKanich, Ronette Gehring, Brad Robert, J Brandon Reinbold, Brad J White |
Abstract |
Dehorning is a common practice involving calves on dairy operations in the United States. However, less than 20% of producers report using analgesics or anesthetics during dehorning. Administration of a systemic analgesic drug at the time of dehorning may be attractive to dairy producers since cornual nerve blocks require 10 - 15 min to take effect and only provide pain relief for a few hours. The primary objectives of this trial were to (1) describe the compartmental pharmacokinetics of meloxicam in calves after IV administration at 0.5 mg/kg and (2) to determine the effect of meloxicam (n = 6) or placebo (n = 6) treatment on serum cortisol response, plasma substance P (SP) concentrations, heart rate (HR), activity and weight gain in calves after scoop dehorning and thermocautery without local anesthesia. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 1% |
Peru | 1 | 1% |
Unknown | 93 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 17 | 18% |
Researcher | 12 | 13% |
Student > Ph. D. Student | 11 | 12% |
Student > Postgraduate | 6 | 6% |
Student > Master | 6 | 6% |
Other | 21 | 22% |
Unknown | 22 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Veterinary Science and Veterinary Medicine | 24 | 25% |
Medicine and Dentistry | 20 | 21% |
Agricultural and Biological Sciences | 16 | 17% |
Unspecified | 3 | 3% |
Nursing and Health Professions | 2 | 2% |
Other | 4 | 4% |
Unknown | 26 | 27% |