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Pharmacokinetics and effect of intravenous meloxicam in weaned Holstein calves following scoop dehorning without local anesthesia

Overview of attention for article published in BMC Veterinary Research, September 2012
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Title
Pharmacokinetics and effect of intravenous meloxicam in weaned Holstein calves following scoop dehorning without local anesthesia
Published in
BMC Veterinary Research, September 2012
DOI 10.1186/1746-6148-8-153
Pubmed ID
Authors

Johann F Coetzee, Ruby A Mosher, Butch KuKanich, Ronette Gehring, Brad Robert, J Brandon Reinbold, Brad J White

Abstract

Dehorning is a common practice involving calves on dairy operations in the United States. However, less than 20% of producers report using analgesics or anesthetics during dehorning. Administration of a systemic analgesic drug at the time of dehorning may be attractive to dairy producers since cornual nerve blocks require 10 - 15 min to take effect and only provide pain relief for a few hours. The primary objectives of this trial were to (1) describe the compartmental pharmacokinetics of meloxicam in calves after IV administration at 0.5 mg/kg and (2) to determine the effect of meloxicam (n = 6) or placebo (n = 6) treatment on serum cortisol response, plasma substance P (SP) concentrations, heart rate (HR), activity and weight gain in calves after scoop dehorning and thermocautery without local anesthesia.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 95 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Peru 1 1%
Unknown 93 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 17 18%
Researcher 12 13%
Student > Ph. D. Student 11 12%
Student > Postgraduate 6 6%
Student > Master 6 6%
Other 21 22%
Unknown 22 23%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 24 25%
Medicine and Dentistry 20 21%
Agricultural and Biological Sciences 16 17%
Unspecified 3 3%
Nursing and Health Professions 2 2%
Other 4 4%
Unknown 26 27%