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TGFβ signalling plays an important role in IL4-induced alternative activation of microglia

Overview of attention for article published in Journal of Neuroinflammation, September 2012
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Title
TGFβ signalling plays an important role in IL4-induced alternative activation of microglia
Published in
Journal of Neuroinflammation, September 2012
DOI 10.1186/1742-2094-9-210
Pubmed ID
Authors

Xiaolai Zhou, Björn Spittau, Kerstin Krieglstein

Abstract

Microglia are the resident immune cells of the central nervous system and are accepted to be involved in a variety of neurodegenerative diseases. Several studies have demonstrated that microglia, like peripheral macrophages, exhibit two entirely different functional activation states, referred to as classical (M1) and alternative (M2) activation. TGFβ is one of the most important anti-inflammatory cytokines and its effect on inhibiting microglia or macrophage classical activation has been extensively studied. However, the role of TGFβ during alternative activation of microglia has not been described yet.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 143 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 <1%
Italy 1 <1%
Unknown 141 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 36 25%
Researcher 24 17%
Student > Bachelor 19 13%
Student > Master 17 12%
Student > Doctoral Student 12 8%
Other 16 11%
Unknown 19 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 39 27%
Medicine and Dentistry 20 14%
Neuroscience 20 14%
Biochemistry, Genetics and Molecular Biology 16 11%
Immunology and Microbiology 5 3%
Other 15 10%
Unknown 28 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 September 2012.
All research outputs
#20,880,816
of 25,654,806 outputs
Outputs from Journal of Neuroinflammation
#2,383
of 2,969 outputs
Outputs of similar age
#147,136
of 187,682 outputs
Outputs of similar age from Journal of Neuroinflammation
#28
of 37 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,969 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.7. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
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We're also able to compare this research output to 37 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.