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Synthesis of an antiviral drug precursor from chitin using a saprophyte as a whole-cell catalyst

Overview of attention for article published in Microbial Cell Factories, December 2011
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  • Good Attention Score compared to outputs of the same age (71st percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

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1 X user
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1 patent

Citations

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12 Dimensions

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40 Mendeley
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Title
Synthesis of an antiviral drug precursor from chitin using a saprophyte as a whole-cell catalyst
Published in
Microbial Cell Factories, December 2011
DOI 10.1186/1475-2859-10-102
Pubmed ID
Authors

Matthias G Steiger, Astrid R Mach-Aigner, Rita Gorsche, Erwin E Rosenberg, Marko D Mihovilovic, Robert L Mach

Abstract

Recent incidents, such as the SARS and influenza epidemics, have highlighted the need for readily available antiviral drugs. One important precursor currently used for the production of Relenza, an antiviral product from GlaxoSmithKline, is N-acetylneuraminic acid (NeuNAc). This substance has a considerably high market price despite efforts to develop cost-reducing (biotechnological) production processes. Hypocrea jecorina (Trichoderma reesei) is a saprophyte noted for its abundant secretion of hydrolytic enzymes and its potential to degrade chitin to its monomer N-acetylglucosamine (GlcNAc). Chitin is considered the second most abundant biomass available on earth and therefore an attractive raw material.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 40 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 23%
Lecturer 5 13%
Professor 4 10%
Student > Doctoral Student 3 8%
Student > Ph. D. Student 3 8%
Other 7 18%
Unknown 9 23%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 23%
Biochemistry, Genetics and Molecular Biology 5 13%
Immunology and Microbiology 2 5%
Chemistry 2 5%
Economics, Econometrics and Finance 2 5%
Other 4 10%
Unknown 16 40%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 September 2012.
All research outputs
#7,173,115
of 22,675,759 outputs
Outputs from Microbial Cell Factories
#489
of 1,582 outputs
Outputs of similar age
#66,858
of 240,356 outputs
Outputs of similar age from Microbial Cell Factories
#16
of 32 outputs
Altmetric has tracked 22,675,759 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 1,582 research outputs from this source. They receive a mean Attention Score of 4.4. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,356 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.