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X Demographics
Mendeley readers
Attention Score in Context
Title |
Functional analysis of transcription factor binding sites in human promoters
|
---|---|
Published in |
Genome Biology, September 2012
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DOI | 10.1186/gb-2012-13-9-r50 |
Pubmed ID | |
Authors |
Troy W Whitfield, Jie Wang, Patrick J Collins, E Christopher Partridge, Shelley Force Aldred, Nathan D Trinklein, Richard M Myers, Zhiping Weng |
Abstract |
The binding of transcription factors to specific locations in the genome is integral to the orchestration of transcriptional regulation in cells. To characterize transcription factor binding site function on a large scale, we predicted and mutagenized 455 binding sites in human promoters. We carried out functional tests on these sites in four different immortalized human cell lines using transient transfections with a luciferase reporter assay, primarily for the transcription factors CTCF, GABP, GATA2, E2F, STAT, and YY1. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 67% |
United States | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 665 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 22 | 3% |
United States | 19 | 3% |
Germany | 5 | <1% |
France | 4 | <1% |
Spain | 4 | <1% |
China | 3 | <1% |
Brazil | 3 | <1% |
Poland | 2 | <1% |
Australia | 2 | <1% |
Other | 16 | 2% |
Unknown | 585 | 88% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 211 | 32% |
Researcher | 173 | 26% |
Student > Master | 75 | 11% |
Student > Bachelor | 42 | 6% |
Professor > Associate Professor | 30 | 5% |
Other | 89 | 13% |
Unknown | 45 | 7% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 373 | 56% |
Biochemistry, Genetics and Molecular Biology | 116 | 17% |
Computer Science | 37 | 6% |
Medicine and Dentistry | 31 | 5% |
Engineering | 10 | 2% |
Other | 42 | 6% |
Unknown | 56 | 8% |
Attention Score in Context
This research output has an Altmetric Attention Score of 18. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 August 2014.
All research outputs
#2,082,139
of 25,374,917 outputs
Outputs from Genome Biology
#1,763
of 4,467 outputs
Outputs of similar age
#13,530
of 187,002 outputs
Outputs of similar age from Genome Biology
#24
of 56 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 187,002 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.