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Rotavirus A-specific single-domain antibodies produced in baculovirus-infected insect larvae are protective in vivo

Overview of attention for article published in BMC Biotechnology, September 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

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1 X user
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2 patents

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84 Mendeley
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Title
Rotavirus A-specific single-domain antibodies produced in baculovirus-infected insect larvae are protective in vivo
Published in
BMC Biotechnology, September 2012
DOI 10.1186/1472-6750-12-59
Pubmed ID
Authors

Silvia Gómez-Sebastián, Maria C Nuñez, Lorena Garaicoechea, Carmen Alvarado, Marina Mozgovoj, Rodrigo Lasa, Alan Kahl, Andres Wigdorovitz, Viviana Parreño, José M Escribano

Abstract

Single-domain antibodies (sdAbs), also known as nanobodies or VHHs, are characterized by high stability and solubility, thus maintaining the affinity and therapeutic value provided by conventional antibodies. Given these properties, VHHs offer a novel alternative to classical antibody approaches. To date, VHHs have been produced mainly in E. coli, yeast, plants and mammalian cells. To apply the single-domain antibodies as a preventive or therapeutic strategy to control rotavirus infections in developing countries (444,000 deaths in children under 5 years of age) has to be minimized their production costs.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Australia 1 1%
Brazil 1 1%
South Africa 1 1%
Canada 1 1%
Argentina 1 1%
Unknown 79 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 26 31%
Student > Ph. D. Student 13 15%
Student > Master 11 13%
Student > Bachelor 8 10%
Student > Doctoral Student 3 4%
Other 9 11%
Unknown 14 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 32%
Biochemistry, Genetics and Molecular Biology 13 15%
Medicine and Dentistry 5 6%
Immunology and Microbiology 4 5%
Veterinary Science and Veterinary Medicine 3 4%
Other 14 17%
Unknown 18 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 August 2022.
All research outputs
#4,256,926
of 23,164,913 outputs
Outputs from BMC Biotechnology
#214
of 941 outputs
Outputs of similar age
#30,138
of 169,877 outputs
Outputs of similar age from BMC Biotechnology
#4
of 18 outputs
Altmetric has tracked 23,164,913 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 941 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.8. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 169,877 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.