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Slugging their way to immortality: driving mammary epithelial cells into a stem cell-like state

Overview of attention for article published in Breast Cancer Research, September 2012
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  • Average Attention Score compared to outputs of the same age and source

Mentioned by

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2 X users
facebook
1 Facebook page

Citations

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4 Dimensions

Readers on

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23 Mendeley
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Title
Slugging their way to immortality: driving mammary epithelial cells into a stem cell-like state
Published in
Breast Cancer Research, September 2012
DOI 10.1186/bcr3188
Pubmed ID
Authors

Kelly Soady, Matthew J Smalley

Abstract

ABSTRACT: Delineating the molecular factors that define and maintain the mammary stem cell state is vital for understanding normal development and tumourigenesis. A recent study by Guo and colleagues identifies two master transcriptional regulators of mammary stem cells, Slug and Sox9, ectopic expression of which confers stem cell attributes on differentiated mammary epithelial cells. Slug and Sox9 expression was also shown to determine in vivo metastatic potential of human breast cancer cell lines. Understanding these factors in the context of normal lineage differentiation is an important step toward elucidating the mammary epithelial cell hierarchy and the origins of cancer stem cells.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 9%
Japan 1 4%
Unknown 20 87%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 43%
Student > Master 4 17%
Student > Ph. D. Student 2 9%
Student > Bachelor 2 9%
Professor 1 4%
Other 1 4%
Unknown 3 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 48%
Biochemistry, Genetics and Molecular Biology 5 22%
Medicine and Dentistry 2 9%
Immunology and Microbiology 1 4%
Nursing and Health Professions 1 4%
Other 0 0%
Unknown 3 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 November 2012.
All research outputs
#15,739,529
of 25,373,627 outputs
Outputs from Breast Cancer Research
#1,386
of 2,052 outputs
Outputs of similar age
#112,619
of 186,815 outputs
Outputs of similar age from Breast Cancer Research
#18
of 26 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,052 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 186,815 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 26 others from the same source and published within six weeks on either side of this one. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.