You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
| Title |
Eurycoma longifolia upregulates osteoprotegerin gene expression in androgen- deficient osteoporosis rat model
|
|---|---|
| Published in |
BMC Complementary Medicine and Therapies, September 2012
|
| DOI | 10.1186/1472-6882-12-152 |
| Pubmed ID | |
| Authors |
Ahmad Nazrun Shuid, Eman El-arabi, Nadia Mohd Effendy, Halimaton Saadiah Abdul Razak, Norliza Muhammad, Norazlina Mohamed, Ima Nirwana Soelaiman |
| Abstract |
Eurycoma longifolia (EL) has been shown recently to protect against bone calcium loss in orchidectomised rats, the model for androgen-deficient osteoporosis. The mechanism behind this is unclear but it may be related to its ability to elevate testosterone levels or it may directly affect bone remodeling. The aim of this study is to determine the mechanism involved by investigating the effects of EL extract on serum testosterone levels, bone biomarkers, biomechanical strength and gene expression of Receptor Activator of Nuclear Factor kappa-B ligand (RANKL), Osteoprotegerin (OPG) and Macrophage-Colony Stimulating Factor (MCSF) in orchidectomised rats. |
Mendeley readers
The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Malaysia | 2 | 4% |
| Unknown | 44 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 8 | 17% |
| Researcher | 8 | 17% |
| Student > Ph. D. Student | 7 | 15% |
| Professor | 4 | 9% |
| Student > Postgraduate | 3 | 7% |
| Other | 7 | 15% |
| Unknown | 9 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 12 | 26% |
| Medicine and Dentistry | 8 | 17% |
| Pharmacology, Toxicology and Pharmaceutical Science | 5 | 11% |
| Biochemistry, Genetics and Molecular Biology | 3 | 7% |
| Chemistry | 3 | 7% |
| Other | 4 | 9% |
| Unknown | 11 | 24% |