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Altered regulatory mechanisms governing cell survival in children affected with clustering of autoimmune disorders

Overview of attention for article published in Italian Journal of Pediatrics, September 2012
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5 Mendeley
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Title
Altered regulatory mechanisms governing cell survival in children affected with clustering of autoimmune disorders
Published in
Italian Journal of Pediatrics, September 2012
DOI 10.1186/1824-7288-38-42
Pubmed ID
Authors

Loredana Palamaro, Giuliana Giardino, Francesca Santamaria, Ugo Ramenghi, Umberto Dianzani, Claudio Pignata

Abstract

Clustering of Autoimmune Diseases (CAD) is now emerging as a novel clinical entity within monogenic immune defects with a high familial occurrence. Aim of this study is to evaluate the regulatory mechanisms governing cell survival, paying a particular attention to Fas-induced apoptosis, in a cohort of 23 children affected with CAD. In 14 patients, Fas stimulation failed to induce cell apoptosis and in 1 case it was associated with Fas gene mutation. Our study highlights the importance to evaluate cell apoptosis in the group of children with CAD, which, with this regard, represents a distinct clinical entity.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 5 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 5 100%

Demographic breakdown

Readers by professional status Count As %
Professor 1 20%
Professor > Associate Professor 1 20%
Researcher 1 20%
Student > Doctoral Student 1 20%
Unknown 1 20%
Readers by discipline Count As %
Medicine and Dentistry 3 60%
Immunology and Microbiology 1 20%
Unknown 1 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 September 2012.
All research outputs
#17,489,487
of 25,654,806 outputs
Outputs from Italian Journal of Pediatrics
#580
of 1,072 outputs
Outputs of similar age
#124,489
of 187,887 outputs
Outputs of similar age from Italian Journal of Pediatrics
#10
of 23 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,072 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 187,887 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 23 others from the same source and published within six weeks on either side of this one. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.