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De novo assembly of highly diverse viral populations

Overview of attention for article published in BMC Genomics, September 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)
  • High Attention Score compared to outputs of the same age and source (81st percentile)

Mentioned by

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13 X users

Citations

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183 Dimensions

Readers on

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268 Mendeley
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3 CiteULike
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Title
De novo assembly of highly diverse viral populations
Published in
BMC Genomics, September 2012
DOI 10.1186/1471-2164-13-475
Pubmed ID
Authors

Xiao Yang, Patrick Charlebois, Sante Gnerre, Matthew G Coole, Niall J Lennon, Joshua Z Levin, James Qu, Elizabeth M Ryan, Michael C Zody, Matthew R Henn

Abstract

Extensive genetic diversity in viral populations within infected hosts and the divergence of variants from existing reference genomes impede the analysis of deep viral sequencing data. A de novo population consensus assembly is valuable both as a single linear representation of the population and as a backbone on which intra-host variants can be accurately mapped. The availability of consensus assemblies and robustly mapped variants are crucial to the genetic study of viral disease progression, transmission dynamics, and viral evolution. Existing de novo assembly techniques fail to robustly assemble ultra-deep sequence data from genetically heterogeneous populations such as viruses into full-length genomes due to the presence of extensive genetic variability, contaminants, and variable sequence coverage.

X Demographics

X Demographics

The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 268 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 5 2%
United States 5 2%
United Kingdom 5 2%
Germany 4 1%
Italy 2 <1%
Canada 2 <1%
Belgium 2 <1%
France 1 <1%
Portugal 1 <1%
Other 7 3%
Unknown 234 87%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 74 28%
Researcher 65 24%
Student > Master 35 13%
Student > Bachelor 22 8%
Student > Doctoral Student 12 4%
Other 38 14%
Unknown 22 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 151 56%
Biochemistry, Genetics and Molecular Biology 46 17%
Computer Science 13 5%
Immunology and Microbiology 7 3%
Medicine and Dentistry 6 2%
Other 18 7%
Unknown 27 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 April 2013.
All research outputs
#4,807,943
of 25,371,288 outputs
Outputs from BMC Genomics
#1,855
of 11,244 outputs
Outputs of similar age
#34,043
of 187,187 outputs
Outputs of similar age from BMC Genomics
#30
of 161 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,244 research outputs from this source. They receive a mean Attention Score of 4.8. This one has done well, scoring higher than 83% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 187,187 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 161 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.