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Serum VEGF levels as predictive marker of bisphosphonate-related osteonecrosis of the jaw

Overview of attention for article published in Journal of Hematology & Oncology, September 2012
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Title
Serum VEGF levels as predictive marker of bisphosphonate-related osteonecrosis of the jaw
Published in
Journal of Hematology & Oncology, September 2012
DOI 10.1186/1756-8722-5-56
Pubmed ID
Authors

Bruno Vincenzi, Andrea Napolitano, Alice Zoccoli, Michele Iuliani, Francesco Pantano, Nicola Papapietro, Vincenzo Denaro, Daniele Santini, Giuseppe Tonini

Abstract

Recent studies have been reported that angiogenesis suppression may play a role in developing bisphosphonate-related osteonecrosis of the jaw (B-ONJ). According to these evidence we evaluated the role of VEGF as predictive marker of B-ONJ onset. Of the 81 patients, 6 developed B-ONJ following bisphosphonate treatment. These patients showed a strongest decrease in VEGF circulating levels at day 7 and at day 21 after the first administration. These data demonstrated for the first time that the anti-angiogenic properties of bisphosphonates are directly linked to B-ONJ pathogenesis and serum VEGF levels could represent an effective early predictive marker.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 2%
Unknown 40 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 5 12%
Student > Ph. D. Student 4 10%
Other 3 7%
Student > Doctoral Student 3 7%
Student > Master 3 7%
Other 11 27%
Unknown 12 29%
Readers by discipline Count As %
Medicine and Dentistry 21 51%
Unspecified 2 5%
Veterinary Science and Veterinary Medicine 1 2%
Agricultural and Biological Sciences 1 2%
Chemical Engineering 1 2%
Other 2 5%
Unknown 13 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 February 2013.
All research outputs
#18,314,922
of 22,678,224 outputs
Outputs from Journal of Hematology & Oncology
#925
of 1,187 outputs
Outputs of similar age
#129,769
of 170,681 outputs
Outputs of similar age from Journal of Hematology & Oncology
#8
of 12 outputs
Altmetric has tracked 22,678,224 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,187 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.4. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 170,681 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.