国環研|妊娠期の化学物質曝露が孫世代の健康に影響を及ぼすメカニズム https://t.co/xKy9Kneze2 https://t.co/jQ9L7kLt31 妊娠期の無機ヒ素暴露が子世代の精子においてレトロトランスポゾンの転移活性調節領域のDNAメチル化を低下させる。この低メチル化は次世代に継承されて疾患の原因となる可能性。
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RT @EpigenChromatin: Gestational arsenic exposure induces site-specific DNA hypomethylation in active retrotransposon subfamilies in offspr…
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Gestational arsenic exposure induces site-specific DNA hypomethylation in active retrotransposon subfamilies in offspring sperm in mice https://t.co/EQWpjzUrAr
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"This is the first report that has identified the specific positions of #methylomes altered in the #retrotransposon elements by #environmental exposure, by genome-wide methylome analysis" https://t.co/CsGFuVBIjf