Title |
The polyomaviruses WUPyV and KIPyV: a retrospective quantitative analysis in patients undergoing hematopoietic stem cell transplantation
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Published in |
Virology Journal, September 2012
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DOI | 10.1186/1743-422x-9-209 |
Pubmed ID | |
Authors |
Nasim Motamedi, Helga Mairhofer, Hans Nitschko, Gundula Jäger, Ulrich H Koszinowski |
Abstract |
The polyomaviruses WUPyV and KIPyV have been detected in various sample types including feces indicating pathogenicity in the gastrointestinal (GI) system. However, quantitative viral load data from other simultaneously collected sample types are missing. As a consequence, primary replication in the GI system cannot be differentiated from swallowed virus from the respiratory tract. Here we present a retrospective quantitative longitudinal analysis in simultaneously harvested specimens from different organ sites of patients undergoing hematopoietic stem cell transplantation (HSCT). This allows the definition of sample types where deoxyribonucleic acid (DNA) detection can be expected and, as a consequence, the identification of their primary replication site. |
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United Kingdom | 1 | 50% |
Australia | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
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Unknown | 12 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 4 | 33% |
Researcher | 2 | 17% |
Other | 1 | 8% |
Student > Master | 1 | 8% |
Unknown | 4 | 33% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 3 | 25% |
Biochemistry, Genetics and Molecular Biology | 2 | 17% |
Engineering | 2 | 17% |
Unknown | 5 | 42% |