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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Advances in the pathogenesis of Alzheimer’s disease: a re-evaluation of amyloid cascade hypothesis
|
|---|---|
| Published in |
Translational Neurodegeneration, September 2012
|
| DOI | 10.1186/2047-9158-1-18 |
| Pubmed ID | |
| Authors |
Suzhen Dong, Yale Duan, Yinghe Hu, Zheng Zhao |
| Abstract |
Alzheimer's disease (AD) is a common neurodegenerative disease characterized clinically by progressive deterioration of memory, and pathologically by histopathological changes including extracellular deposits of amyloid-beta (A-beta) peptides forming senile plaques (SP) and the intracellular neurofibrillary tangles (NFT) of hyperphosphorylated tau in the brain. This review focused on the new developments of amyloid cascade hypothesis with details on the production, metabolism and clearance of A-beta, and the key roles of some important A-beta-related genes in the pathological processes of AD. The most recent research advances in genetics, neuropathology and pathogenesis of the disease were also discussed. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 238 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Belgium | 2 | <1% |
| Egypt | 1 | <1% |
| Korea, Republic of | 1 | <1% |
| Mexico | 1 | <1% |
| Spain | 1 | <1% |
| Unknown | 232 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 51 | 21% |
| Student > Bachelor | 49 | 21% |
| Student > Ph. D. Student | 43 | 18% |
| Researcher | 20 | 8% |
| Student > Postgraduate | 12 | 5% |
| Other | 33 | 14% |
| Unknown | 30 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 46 | 19% |
| Medicine and Dentistry | 46 | 19% |
| Biochemistry, Genetics and Molecular Biology | 30 | 13% |
| Neuroscience | 26 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 17 | 7% |
| Other | 37 | 16% |
| Unknown | 36 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 September 2012.
All research outputs
#17,285,036
of 25,371,288 outputs
Outputs from Translational Neurodegeneration
#334
of 384 outputs
Outputs of similar age
#124,746
of 189,226 outputs
Outputs of similar age from Translational Neurodegeneration
#3
of 4 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 384 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 29.7. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 189,226 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 4 others from the same source and published within six weeks on either side of this one.