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Antitumor activity of motesanib alone and in combination with cisplatin or docetaxel in multiple human non–small-cell lung cancer xenograft models

Overview of attention for article published in Molecular Cancer, September 2012
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1 X user

Citations

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Title
Antitumor activity of motesanib alone and in combination with cisplatin or docetaxel in multiple human non–small-cell lung cancer xenograft models
Published in
Molecular Cancer, September 2012
DOI 10.1186/1476-4598-11-70
Pubmed ID
Authors

Angela Coxon, Beth Ziegler, Stephen Kaufman, Man Xu, Hongyu Wang, Dawn Weishuhn, Joanna Schmidt, Heather Sweet, Charlie Starnes, Douglas Saffran, Anthony Polverino

Abstract

Non-small-cell lung cancer (NSCLC) is categorized into various histologic subtypes that play an important role in prognosis and treatment outcome. We investigated the antitumor activity of motesanib, a selective antagonist of vascular endothelial growth factor receptors (VEGFR) 1, 2, and 3, platelet-derived growth factor receptor, and Kit, alone and combined with chemotherapy in five human NSCLC xenograft models (A549, Calu-6, NCI-H358, NCI-H1299, and NCI-H1650) containing diverse genetic mutations.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 3%
Netherlands 1 3%
United States 1 3%
Unknown 28 90%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 45%
Student > Ph. D. Student 6 19%
Student > Postgraduate 2 6%
Other 1 3%
Unspecified 1 3%
Other 3 10%
Unknown 4 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 29%
Medicine and Dentistry 5 16%
Biochemistry, Genetics and Molecular Biology 5 16%
Computer Science 3 10%
Pharmacology, Toxicology and Pharmaceutical Science 2 6%
Other 3 10%
Unknown 4 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 September 2012.
All research outputs
#22,759,452
of 25,374,647 outputs
Outputs from Molecular Cancer
#1,679
of 1,919 outputs
Outputs of similar age
#169,773
of 188,989 outputs
Outputs of similar age from Molecular Cancer
#12
of 13 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,919 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 188,989 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.