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Molecular predictors of response to tyrosine kinase inhibitors in patients with Non-Small-Cell Lung Cancer

Overview of attention for article published in Journal of Experimental & Clinical Cancer Research, September 2012
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Mentioned by

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1 Google+ user

Citations

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19 Dimensions

Readers on

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37 Mendeley
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Title
Molecular predictors of response to tyrosine kinase inhibitors in patients with Non-Small-Cell Lung Cancer
Published in
Journal of Experimental & Clinical Cancer Research, September 2012
DOI 10.1186/1756-9966-31-77
Pubmed ID
Authors

Samuel Murray, Vasilios Karavasilis, Mattheos Bobos, Evangelia Razis, Savvas Papadopoulos, Christos Christodoulou, Paris Kosmidis, George Fountzilas

Abstract

Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) have become a treatment option in non-small-cell lung cancer (NSCLC) patients. However, despite their use in this disease, a significant number of patients will eventually develop resistance and relapse. In this study, we aimed to characterize several molecular events involved in potential resistance mechanisms to anti-EGFR treatment and correlate our findings with clinical outcome.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 37 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Unknown 36 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 19%
Other 5 14%
Student > Bachelor 4 11%
Student > Ph. D. Student 4 11%
Lecturer 3 8%
Other 10 27%
Unknown 4 11%
Readers by discipline Count As %
Medicine and Dentistry 12 32%
Agricultural and Biological Sciences 8 22%
Biochemistry, Genetics and Molecular Biology 5 14%
Nursing and Health Professions 3 8%
Pharmacology, Toxicology and Pharmaceutical Science 3 8%
Other 1 3%
Unknown 5 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 September 2012.
All research outputs
#17,285,668
of 25,374,647 outputs
Outputs from Journal of Experimental & Clinical Cancer Research
#1,246
of 2,378 outputs
Outputs of similar age
#124,643
of 188,989 outputs
Outputs of similar age from Journal of Experimental & Clinical Cancer Research
#2
of 7 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,378 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 188,989 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than 5 of them.