Title |
Performance comparison of phenotypic and molecular methods for detection and differentiation of Candida albicans and Candida dubliniensis
|
---|---|
Published in |
BMC Infectious Diseases, September 2012
|
DOI | 10.1186/1471-2334-12-230 |
Pubmed ID | |
Authors |
Suhail Ahmad, Ziauddin Khan, Mohammad Asadzadeh, Ajmal Theyyathel, Rachel Chandy |
Abstract |
Candida albicans is the most pathogenic Candida species but shares many phenotypic features with Candida dubliniensis and may, therefore, be misidentified in clinical microbiology laboratories. Candidemia cases due to C. dubliniensis are increasingly being reported in recent years. Accurate identification is warranted since mortality rates are highest for C. albicans infections, however, C. dubliniensis has the propensity to develop resistance against azoles more easily. We developed a duplex PCR assay for rapid detection and differentiation of C. albicans from C. dubliniensis for resource-poor settings equipped with basic PCR technology and compared its performance with three phenotypic methods. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | 2% |
Unknown | 61 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 12 | 19% |
Student > Bachelor | 7 | 11% |
Researcher | 6 | 10% |
Student > Ph. D. Student | 6 | 10% |
Student > Postgraduate | 5 | 8% |
Other | 17 | 27% |
Unknown | 9 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 25 | 40% |
Medicine and Dentistry | 12 | 19% |
Immunology and Microbiology | 6 | 10% |
Biochemistry, Genetics and Molecular Biology | 6 | 10% |
Veterinary Science and Veterinary Medicine | 2 | 3% |
Other | 2 | 3% |
Unknown | 9 | 15% |