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Dark adaptation in relation to choroidal thickness in healthy young subjects: a cross-sectional, observational study

Overview of attention for article published in BMC Ophthalmology, July 2016
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Title
Dark adaptation in relation to choroidal thickness in healthy young subjects: a cross-sectional, observational study
Published in
BMC Ophthalmology, July 2016
DOI 10.1186/s12886-016-0273-6
Pubmed ID
Authors

Inger Christine Munch, Cigdem Altuntas, Xiao Qiang Li, Gregory R. Jackson, Oliver Niels Klefter, Michael Larsen

Abstract

Dark adaptation is an energy-requiring process in the outer retina nourished by the profusely perfused choroid. We hypothesized that variations in choroidal thickness might affect the rate of dark adaptation. Cross-sectional, observational study of 42 healthy university students (mean age 25 ± 2.0 years, 29 % men) who were examined using an abbreviated automated dark adaptometry protocol with a 2° diameter stimulus centered 5° above the point of fixation. The early, linear part of the rod-mediated dark adaptation curve was analyzed to extract the time required to reach a sensitivity of 5.0 × 10(-3) cd/m2 (time to rod intercept) and the slope (rod adaptation rate). The choroid was imaged using enhanced-depth imaging spectral-domain optical coherence tomography (EDI-OCT). The time to the rod intercept was 7.3 ± 0.94 (range 5.1 - 10.2) min. Choroidal thickness 2.5° above the fovea was 348 ± 104 (range 153-534) μm. There was no significant correlation between any of the two measures of rod-mediated dark adaptation and choroidal thickness (time to rod intercept versus choroidal thickness 0.072 (CI95 -0.23 to 0.38) min/100 μm, P = 0.64, adjusted for age and sex). There was no association between the time-to-rod-intercept or the dark adaptation rate and axial length, refraction, gender or age. Choroidal thickness, refraction and ocular axial length had no detectable effect on rod-mediated dark adaptation in healthy young subjects. Our results do not support that variations in dark adaptation can be attributed to variations in choroidal thickness.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 24 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 21%
Researcher 4 17%
Student > Bachelor 3 13%
Student > Ph. D. Student 3 13%
Lecturer > Senior Lecturer 2 8%
Other 0 0%
Unknown 7 29%
Readers by discipline Count As %
Medicine and Dentistry 7 29%
Nursing and Health Professions 3 13%
Agricultural and Biological Sciences 1 4%
Environmental Science 1 4%
Economics, Econometrics and Finance 1 4%
Other 3 13%
Unknown 8 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 July 2016.
All research outputs
#6,958,388
of 22,880,691 outputs
Outputs from BMC Ophthalmology
#311
of 2,359 outputs
Outputs of similar age
#115,464
of 354,317 outputs
Outputs of similar age from BMC Ophthalmology
#7
of 42 outputs
Altmetric has tracked 22,880,691 research outputs across all sources so far. This one has received more attention than most of these and is in the 69th percentile.
So far Altmetric has tracked 2,359 research outputs from this source. They receive a mean Attention Score of 2.7. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 354,317 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 42 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.