↓ Skip to main content

Is the C-terminal insertional signal in Gram-negative bacterial outer membrane proteins species-specific or not?

Overview of attention for article published in BMC Genomics, September 2012
Altmetric Badge

About this Attention Score

  • Average Attention Score compared to outputs of the same age
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

twitter
2 X users

Readers on

mendeley
71 Mendeley
citeulike
2 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Is the C-terminal insertional signal in Gram-negative bacterial outer membrane proteins species-specific or not?
Published in
BMC Genomics, September 2012
DOI 10.1186/1471-2164-13-510
Pubmed ID
Authors

Nagarajan Paramasivam, Michael Habeck, Dirk Linke

Abstract

In Gram-negative bacteria, the outer membrane is composed of an asymmetric lipid bilayer of phopspholipids and lipopolysaccharides, and the transmembrane proteins that reside in this membrane are almost exclusively β-barrel proteins. These proteins are inserted into the membrane by a highly conserved and essential machinery, the BAM complex. It recognizes its substrates, unfolded outer membrane proteins (OMPs), through a C-terminal motif that has been speculated to be species-specific, based on theoretical and experimental results from only two species, Escherichia coli and Neisseria meningitidis, where it was shown on the basis of individual sequences and motifs that OMPs from the one cannot easily be over expressed in the other, unless the C-terminal motif was adapted. In order to determine whether this species specificity is a general phenomenon, we undertook a large-scale bioinformatics study on all predicted OMPs from 437 fully sequenced proteobacterial strains.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 71 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
New Zealand 1 1%
India 1 1%
Germany 1 1%
Unknown 68 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 27 38%
Researcher 21 30%
Student > Master 5 7%
Student > Postgraduate 4 6%
Student > Bachelor 3 4%
Other 6 8%
Unknown 5 7%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 26 37%
Agricultural and Biological Sciences 25 35%
Immunology and Microbiology 7 10%
Environmental Science 1 1%
Computer Science 1 1%
Other 3 4%
Unknown 8 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 November 2012.
All research outputs
#14,607,238
of 22,679,690 outputs
Outputs from BMC Genomics
#6,069
of 10,615 outputs
Outputs of similar age
#102,912
of 171,749 outputs
Outputs of similar age from BMC Genomics
#70
of 119 outputs
Altmetric has tracked 22,679,690 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,615 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 42nd percentile – i.e., 42% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 171,749 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 119 others from the same source and published within six weeks on either side of this one. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.