Title |
Plasma proteomics shows an elevation of the anti-inflammatory protein APOA-IV in chronic equine laminitis
|
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Published in |
BMC Veterinary Research, September 2012
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DOI | 10.1186/1746-6148-8-179 |
Pubmed ID | |
Authors |
Samantha M Steelman, Bhanu P Chowdhary |
Abstract |
Equine laminitis is a devastating disease that causes severe pain in afflicted horses and places a major economic burden on the horse industry. In acute laminitis, the disintegration of the dermal-epidermal junction can cause the third phalanx to detach from the hoof wall, leaving the horse unable to bear weight on the affected limbs. Horses that survive the acute phase transition into a chronic form of laminitis, which is often termed "founder". Some evidence suggests that chronic laminar inflammation might be associated with alterations in the endocrine and immune systems. We investigated this broad hypothesis by using DIGE to assess global differences in the plasma proteome between horses with chronic laminitis and controls. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Science communicators (journalists, bloggers, editors) | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 50 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 7 | 14% |
Student > Bachelor | 7 | 14% |
Student > Doctoral Student | 5 | 10% |
Researcher | 4 | 8% |
Professor > Associate Professor | 4 | 8% |
Other | 6 | 12% |
Unknown | 17 | 34% |
Readers by discipline | Count | As % |
---|---|---|
Veterinary Science and Veterinary Medicine | 12 | 24% |
Medicine and Dentistry | 10 | 20% |
Agricultural and Biological Sciences | 4 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
Economics, Econometrics and Finance | 1 | 2% |
Other | 3 | 6% |
Unknown | 19 | 38% |