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Epigenetics: filling in the 'heritability gap' and identifying gene-environment interactions in ulcerative colitis

Overview of attention for article published in Genome Medicine, September 2012
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Title
Epigenetics: filling in the 'heritability gap' and identifying gene-environment interactions in ulcerative colitis
Published in
Genome Medicine, September 2012
DOI 10.1186/gm373
Pubmed ID
Authors

Eamonn MM Quigley

Abstract

Ulcerative colitis is a common inflammatory bowel disorder associated with considerable morbidity. Its incidence is increasing worldwide. While familial aggregation of ulcerative colitis is a common phenomenon, genome-wide association studies, identifying a plethora of associated genes, have failed to reveal a unifying causative pathway. The well-documented impact of a number of environmental factors on disease occurrence and natural history suggests a major role for epigenetic events. The epigenome-wide association study discussed in this highlight has revealed novel loci linked to colitis and has provided unique insights into the pathophysiology of this disorder information that could translate into new therapeutic approaches.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Hungary 1 3%
United States 1 3%
South Africa 1 3%
Unknown 27 90%

Demographic breakdown

Readers by professional status Count As %
Student > Master 6 20%
Student > Ph. D. Student 5 17%
Researcher 4 13%
Professor 3 10%
Other 3 10%
Other 7 23%
Unknown 2 7%
Readers by discipline Count As %
Medicine and Dentistry 12 40%
Agricultural and Biological Sciences 8 27%
Biochemistry, Genetics and Molecular Biology 5 17%
Immunology and Microbiology 1 3%
Arts and Humanities 1 3%
Other 0 0%
Unknown 3 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 September 2012.
All research outputs
#20,656,820
of 25,374,647 outputs
Outputs from Genome Medicine
#1,509
of 1,585 outputs
Outputs of similar age
#148,929
of 190,957 outputs
Outputs of similar age from Genome Medicine
#14
of 16 outputs
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We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.