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X Demographics
Mendeley readers
Attention Score in Context
Title |
The potential for selective pharmacological therapies through biased receptor signaling
|
---|---|
Published in |
BMC Pharmacology and Toxicology, August 2012
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DOI | 10.1186/2050-6511-13-3 |
Pubmed ID | |
Authors |
Terry Kenakin |
Abstract |
The discovery that not all agonists uniformly activate cellular signaling pathways (biased signaling) has greatly changed the drug discovery process for agonists and the strategy for treatment of disease with agonists. Technological advances have enabled complex receptor behaviors to be viewed independently and through these assays, the bias for an agonist can be quantified. It is predicted that therapeutic phenotypes will be linked, through translational studies, to quantified scales of bias to guide medicinal chemists in the drug discovery process. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 3% |
Canada | 2 | 3% |
Bulgaria | 1 | 1% |
Netherlands | 1 | 1% |
Unknown | 63 | 91% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 18 | 26% |
Student > Ph. D. Student | 13 | 19% |
Student > Bachelor | 8 | 12% |
Student > Doctoral Student | 5 | 7% |
Other | 5 | 7% |
Other | 10 | 14% |
Unknown | 10 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 18 | 26% |
Medicine and Dentistry | 10 | 14% |
Biochemistry, Genetics and Molecular Biology | 8 | 12% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 7% |
Neuroscience | 5 | 7% |
Other | 12 | 17% |
Unknown | 11 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 October 2012.
All research outputs
#3,956,284
of 22,679,690 outputs
Outputs from BMC Pharmacology and Toxicology
#65
of 438 outputs
Outputs of similar age
#28,041
of 167,391 outputs
Outputs of similar age from BMC Pharmacology and Toxicology
#2
of 8 outputs
Altmetric has tracked 22,679,690 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 438 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.3. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 167,391 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 6 of them.