Title |
“Herbal seizures” – atypical symptoms after ibogaine intoxication: a case report
|
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Published in |
Journal of Medical Case Reports, October 2015
|
DOI | 10.1186/s13256-015-0731-4 |
Pubmed ID | |
Authors |
Lorenz Breuer, Burkhard S. Kasper, Bernd Schwarze, Juergen M. Gschossmann, Johannes Kornhuber, Helge H. Müller |
Abstract |
Misuse of various new psychotropic substances such as ibogaine is increasing rapidly. Knowledge of their negative side effects is sparse. We present a case of intoxication with the herbal substance ibogaine in a 22-year-old white man. After taking a cumulative dose of 38 g (taken in two doses), he developed visual memories, nausea and vomiting. He developed a generalized tonic-clonic seizure with additional grand mal seizures. He was treated with midazolam and levetiracetam. Extended drug screenings and computed tomography and magnetic resonance imaging findings were all negative. Knowledge of the side effects of ibogaine has mainly come from reports of cardiovascular complications; seizures are rarely mentioned and experimental findings are inconsistent. It seems that ibogaine acts like a proconvulsive drug at high doses. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 53 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 9 | 17% |
Other | 7 | 13% |
Student > Master | 6 | 11% |
Student > Doctoral Student | 5 | 9% |
Student > Postgraduate | 4 | 8% |
Other | 8 | 15% |
Unknown | 14 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 14 | 26% |
Pharmacology, Toxicology and Pharmaceutical Science | 7 | 13% |
Psychology | 6 | 11% |
Nursing and Health Professions | 3 | 6% |
Agricultural and Biological Sciences | 3 | 6% |
Other | 6 | 11% |
Unknown | 14 | 26% |