↓ Skip to main content

The relationship between the hierarchical position of proteins in the human signal transduction network and their rate of evolution

Overview of attention for article published in BMC Ecology and Evolution, September 2012
Altmetric Badge

About this Attention Score

  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

Mentioned by

twitter
2 X users
wikipedia
1 Wikipedia page

Citations

dimensions_citation
22 Dimensions

Readers on

mendeley
53 Mendeley
citeulike
1 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
The relationship between the hierarchical position of proteins in the human signal transduction network and their rate of evolution
Published in
BMC Ecology and Evolution, September 2012
DOI 10.1186/1471-2148-12-192
Pubmed ID
Authors

David Alvarez-Ponce

Abstract

Proteins evolve at disparate rates, as a result of the action of different types and strengths of evolutionary forces. An open question in evolutionary biology is what factors are responsible for this variability. In general, proteins whose function has a great impact on organisms' fitness are expected to evolve under stronger selective pressures. In biosynthetic pathways, upstream genes usually evolve under higher levels of selective constraint than those acting at the downstream part, as a result of their higher hierarchical position. Similar observations have been made in transcriptional regulatory networks, whose upstream elements appear to be more essential and subject to selection. Less well understood is, however, how selective pressures distribute along signal transduction pathways.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 2%
Netherlands 1 2%
Unknown 51 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 28%
Student > Ph. D. Student 13 25%
Professor > Associate Professor 6 11%
Professor 4 8%
Student > Postgraduate 4 8%
Other 7 13%
Unknown 4 8%
Readers by discipline Count As %
Agricultural and Biological Sciences 35 66%
Biochemistry, Genetics and Molecular Biology 8 15%
Environmental Science 1 2%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Computer Science 1 2%
Other 1 2%
Unknown 6 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 August 2023.
All research outputs
#6,753,656
of 25,373,627 outputs
Outputs from BMC Ecology and Evolution
#1,503
of 3,714 outputs
Outputs of similar age
#49,575
of 191,377 outputs
Outputs of similar age from BMC Ecology and Evolution
#16
of 51 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 3,714 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.5. This one has gotten more attention than average, scoring higher than 58% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 191,377 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.