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Effect of maternal Helicobacter Pylori infection on birth weight in an urban community in Uganda

Overview of attention for article published in BMC Pregnancy and Childbirth, July 2016
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Title
Effect of maternal Helicobacter Pylori infection on birth weight in an urban community in Uganda
Published in
BMC Pregnancy and Childbirth, July 2016
DOI 10.1186/s12884-016-0950-8
Pubmed ID
Authors

Ronald Wanyama, Mike N. Kagawa, Kenneth C. Opio, Rhona K. Baingana

Abstract

Helicobacter pylori, a widespread infection particularly in developing countries has been associated with many adverse effects during pregnancy including hyperemesis gravidarum, neural tube defects in newborns, intrauterine fetal growth restriction and miscarriage. We sought to document the effects of H. pylori infection on birth weight in a low-income setting in Kampala, Uganda. This was a prospective cohort study conducted in Kampala between May 2012 and May 2013. The participants were H. pylori positive and H. pylori negative HIV negative primigravidae and secundigravidae. Recruitment was at ≤18 gestation weeks and follow up assessments were carried out at 26 and 36 gestation weeks and soon after delivery. H. pylori infection was determined using H. pylori stool antigen test. Maternal weight and height were measured, and body mass index (BMI) and gestational weight gain were calculated. Only term and live babies were considered. Low birth weight (LBW) was defined as a birth weight of <2500 gram. A total of 221 participants were enrolled with mean ± standard deviation (SD) age of 20.9 ± 2.7 years. The mean ± SD gestation age at delivery was 39.4 ± 1.0 weeks. Primigravidae were 61.5 % (n = 188) and 52.9 % (n = 117) of the participants were positive for H. pylori infection. Low pre-pregnancy BMI (<18.5 kg/m(2)) was recorded in 14.6 % (n = 28) while 38 % (n = 73) had a height <156 cm at recruitment. Of the infants born to the participants, 13.6 % (n = 26) had low birth weight (<2500 gram). Independent predictors for LBW were the mother being positive for H. pylori infection (odds ratio, OR, 3.6, 95 % CI 1.1 - 11.5; P = 0.031) maternal height at recruitment <156 cm (OR 3.4, 95 % CI 1.4-8.2; P = 0.008) and maternal weight gain rates <0.3 kg/week during the 2(nd) and 3(rd) trimesters (OR 3.8, 95 % CI 1.0-14.1; P = 0.044). H. pylori infection is associated with LBW among primigravidae and secundigravidae in Kampala, Uganda.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 88 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 14 16%
Student > Bachelor 14 16%
Researcher 9 10%
Student > Postgraduate 5 6%
Student > Ph. D. Student 4 5%
Other 7 8%
Unknown 35 40%
Readers by discipline Count As %
Medicine and Dentistry 21 24%
Nursing and Health Professions 11 13%
Immunology and Microbiology 5 6%
Biochemistry, Genetics and Molecular Biology 4 5%
Social Sciences 3 3%
Other 5 6%
Unknown 39 44%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 July 2016.
All research outputs
#18,465,988
of 22,880,691 outputs
Outputs from BMC Pregnancy and Childbirth
#3,483
of 4,208 outputs
Outputs of similar age
#271,353
of 354,668 outputs
Outputs of similar age from BMC Pregnancy and Childbirth
#82
of 99 outputs
Altmetric has tracked 22,880,691 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,208 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one is in the 9th percentile – i.e., 9% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 354,668 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 99 others from the same source and published within six weeks on either side of this one. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.