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Efficacy and safety of venous angioplasty of the extracranial veins for multiple sclerosis. Brave dreams study (brain venous drainage exploited against multiple sclerosis): study protocol for a…

Overview of attention for article published in Trials, October 2012
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Title
Efficacy and safety of venous angioplasty of the extracranial veins for multiple sclerosis. Brave dreams study (brain venous drainage exploited against multiple sclerosis): study protocol for a randomized controlled trial
Published in
Trials, October 2012
DOI 10.1186/1745-6215-13-183
Pubmed ID
Authors

Paolo Zamboni, Antonio Bertolotto, Paolo Boldrini, Patrizia Cenni, Roberto D’Alessandro, Roberto D’Amico, Massimo Del Sette, Roberto Galeotti, Stefania Galimberti, Alessandro Liberati, Luca Massacesi, Donato Papini, Fabrizio Salvi, Silvana Simi, Andrea Stella, Luigi Tesio, Maria Grazia Valsecchi, Graziella Filippini, Chair of the Steering Committee

Abstract

Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system with a disabling progressive course. Chronic cerebrospinal venous insufficiency (CCSVI) has recently been described as a vascular condition characterized by restricted venous outflow from the brain, mainly due to blockages of the internal jugular and azygos veins. Despite a wide variability among studies, it has been found to be associated with MS. Data from a few small case series suggest possible improvement of the clinical course and quality of life by performing percutaneous balloon angioplasty (PTA) of the stenotic veins.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 168 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Uruguay 1 <1%
Unknown 166 99%

Demographic breakdown

Readers by professional status Count As %
Student > Master 25 15%
Student > Ph. D. Student 23 14%
Student > Bachelor 22 13%
Researcher 20 12%
Other 8 5%
Other 28 17%
Unknown 42 25%
Readers by discipline Count As %
Medicine and Dentistry 53 32%
Psychology 19 11%
Nursing and Health Professions 11 7%
Neuroscience 9 5%
Sports and Recreations 8 5%
Other 16 10%
Unknown 52 31%