Title |
Characterization of the stem cell system of the acoel Isodiametra pulchra
|
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Published in |
BMC Developmental Biology, December 2009
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DOI | 10.1186/1471-213x-9-69 |
Pubmed ID | |
Authors |
Katrien De Mulder, Georg Kuales, Daniela Pfister, Maxime Willems, Bernhard Egger, Willi Salvenmoser, Marlene Thaler, Anne-Kathrin Gorny, Martina Hrouda, Gaëtan Borgonie, Peter Ladurner |
Abstract |
Tissue plasticity and a substantial regeneration capacity based on stem cells are the hallmark of several invertebrate groups such as sponges, cnidarians and Platyhelminthes. Traditionally, Acoela were seen as an early branching clade within the Platyhelminthes, but became recently positioned at the base of the Bilateria. However, little is known on how the stem cell system in this new phylum is organized. In this study, we wanted to examine if Acoela possess a neoblast-like stem cell system that is responsible for development, growth, homeostasis and regeneration. |
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