Title |
Toxic epidermal necrolysis, DRESS, AGEP: Do overlap cases exist?
|
---|---|
Published in |
Orphanet Journal of Rare Diseases, September 2012
|
DOI | 10.1186/1750-1172-7-72 |
Pubmed ID | |
Authors |
Sophie Bouvresse, Laurence Valeyrie-Allanore, Nicolas Ortonne, Marie Pauline Konstantinou, Sylvia H Kardaun, Martine Bagot, Pierre Wolkenstein, Jean-Claude Roujeau |
Abstract |
Severe cutaneous adverse reactions to drugs (SCARs) include acute generalized exanthematous pustulosis (AGEP), drug reaction with eosinophilia and systemic symptoms (DRESS) and epidermal necrolysis (Stevens-Johnson syndrome-toxic epidermal necrolysis [SJS-TEN]). Because of the varied initial presentation of such adverse drug reactions, diagnosis may be difficult and suggests overlap among SCARs. Overlapping SCARs are defined as cases fulfilling the criteria for definite or probable diagnosis of at least 2 ADRs according to scoring systems for AGEP, DRESS and SJS-TEN. We aimed to evaluate the prevalence of overlap among SCARs among cases in the referral hospital in France. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 2 | 67% |
Netherlands | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Korea, Republic of | 2 | 3% |
Portugal | 1 | 1% |
Unknown | 77 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 15 | 19% |
Student > Postgraduate | 10 | 13% |
Researcher | 8 | 10% |
Student > Doctoral Student | 8 | 10% |
Student > Master | 7 | 9% |
Other | 15 | 19% |
Unknown | 17 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 41 | 51% |
Pharmacology, Toxicology and Pharmaceutical Science | 7 | 9% |
Biochemistry, Genetics and Molecular Biology | 2 | 3% |
Agricultural and Biological Sciences | 2 | 3% |
Business, Management and Accounting | 1 | 1% |
Other | 5 | 6% |
Unknown | 22 | 28% |