Title |
Frnakenstein: multiple target inverse RNA folding
|
---|---|
Published in |
BMC Bioinformatics, October 2012
|
DOI | 10.1186/1471-2105-13-260 |
Pubmed ID | |
Authors |
Rune B Lyngsø, James WJ Anderson, Elena Sizikova, Amarendra Badugu, Tomas Hyland, Jotun Hein |
Abstract |
RNA secondary structure prediction, or folding, is a classic problem in bioinformatics: given a sequence of nucleotides, the aim is to predict the base pairs formed in its three dimensional conformation. The inverse problem of designing a sequence folding into a particular target structure has only more recently received notable interest. With a growing appreciation and understanding of the functional and structural properties of RNA motifs, and a growing interest in utilising biomolecules in nano-scale designs, the interest in the inverse RNA folding problem is bound to increase. However, whereas the RNA folding problem from an algorithmic viewpoint has an elegant and efficient solution, the inverse RNA folding problem appears to be hard. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
France | 2 | 40% |
Denmark | 1 | 20% |
Unknown | 2 | 40% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 60% |
Scientists | 2 | 40% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 5% |
France | 1 | 3% |
South Africa | 1 | 3% |
Unknown | 36 | 90% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 10 | 25% |
Student > Ph. D. Student | 7 | 18% |
Student > Master | 6 | 15% |
Professor | 4 | 10% |
Student > Bachelor | 3 | 8% |
Other | 4 | 10% |
Unknown | 6 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 19 | 48% |
Computer Science | 7 | 18% |
Biochemistry, Genetics and Molecular Biology | 3 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 3% |
Earth and Planetary Sciences | 1 | 3% |
Other | 2 | 5% |
Unknown | 7 | 18% |