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Mendeley readers
Attention Score in Context
| Title |
A genome-wide signature of glucocorticoid receptor binding in neuronal PC12 cells
|
|---|---|
| Published in |
BMC Neuroscience, October 2012
|
| DOI | 10.1186/1471-2202-13-118 |
| Pubmed ID | |
| Authors |
J Annelies E Polman, Jennifer E Welten, Danny S Bosch, Robert T de Jonge, Judit Balog, Silvère M van der Maarel, E Ronald de Kloet, Nicole A Datson |
| Abstract |
Glucocorticoids, secreted by the adrenals in response to stress, profoundly affect structure and plasticity of neurons. Glucocorticoid action in neurons is mediated by glucocorticoid receptors (GR) that operate as transcription factors in the regulation of gene expression and either bind directly to genomic glucocorticoid response elements (GREs) or indirectly to the genome via interactions with bound transcription factors. These two modes of action, respectively called transactivation and transrepression, result in the regulation of a wide variety of genes important for neuronal function. The objective of the present study was to identify genome-wide glucocorticoid receptor binding sites in neuronal PC12 cells using Chromatin ImmunoPrecipitation combined with next generation sequencing (ChIP-Seq). |
Mendeley readers
The data shown below were compiled from readership statistics for 136 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | 1% |
| United States | 1 | <1% |
| China | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 131 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 39 | 29% |
| Researcher | 28 | 21% |
| Student > Master | 14 | 10% |
| Student > Bachelor | 13 | 10% |
| Professor | 5 | 4% |
| Other | 14 | 10% |
| Unknown | 23 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 43 | 32% |
| Biochemistry, Genetics and Molecular Biology | 29 | 21% |
| Neuroscience | 18 | 13% |
| Medicine and Dentistry | 5 | 4% |
| Chemistry | 4 | 3% |
| Other | 9 | 7% |
| Unknown | 28 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 October 2012.
All research outputs
#20,169,675
of 22,681,577 outputs
Outputs from BMC Neuroscience
#1,051
of 1,240 outputs
Outputs of similar age
#153,340
of 172,467 outputs
Outputs of similar age from BMC Neuroscience
#23
of 25 outputs
Altmetric has tracked 22,681,577 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,240 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 172,467 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.